These are snippets from the current literature
Seeds make-up around 10 to 15% of the total fruit weight and have high carbohydrate and protein contents.
Fresh seeds cannot kept for a long time, seed flour can be made.
Reported protein, crude lipids and carbohydrates contents of jackfruit seeds were 31.9%, 1.3% and 66.2% (dwb), respectively, according to one analysis. Another found Protein, crude lipids and carbohydrates content were 17.8-18.3%, 2.1-2.5% and 76.1% (dwb), respectively. Either way
Either way, seeds look like a good source of protein.
Jackfruit seeds contains 2 lectins known as jacalin and artocarpin. Jacalin has potential application for evaluation of the immunological status of a patient infected with human immunodeficiency virus.
Jacalin, a noncytotoxic plant lectin extracted from the seeds of a species of Jackfruit called Artocarpus integrifolia
Tumor-associated macrophages (TAMs) have an ambiguous and complex role in the carcinogenic process, since these cells can be polarized into different phenotypes (proinflammatory, antitumor cells or anti-inflammatory, protumor cells) by the tumor microenvironment.
Given that the interactions between tumor cells and TAMs involve several players, a better understanding of the function and regulation of TAMs is crucial to interfere with their differentiation in attempts to skew TAM polarization into cells with a proinflammatory antitumor phenotype. In this study, we investigated the modulation of macrophage tumoricidal activities by the lectin jacalin.
Jacalin bound to macrophage surface and induced the expression and/or release of mainly proinflammatory cytokines via NF-KB signaling, as well as increased iNOS mRNA expression, suggesting that the lectin polarizes macrophages toward the antitumor phenotype.
Therefore, tumoricidal activities of jacalin-stimulated macrophages were evaluated. High rates of tumor cell (human colon, HT-29, and breast, MCF-7, cells) apoptosis were observed upon incubation with supernatants from jacalin-stimulated macrophages.
Taken together, these results indicate that jacalin, by exerting a proinflammatory activity, can direct macrophages to an antitumor phenotype. Deep knowledge of the regulation of TAM functions is essential for the development of innovative anticancer strategies.
Jackfruit flesh © Toxno
Artocarpus heterophyllus seeds showed antioxidant activity.
Prenylflavones, isolated from Artocarpus heterophyllus was found to serve as powerful antioxidants against lipid peroxidation.
A study revealed the potency of phytochemicals from Artocarpus heterophyllus in the prevention of dental caries.
The hot water extracts of Artocarpus heterophyllus leaves were investigated for its anti-diabetic activity on normal human subjects and diabetic patients. The extracts appreciably improved glucose tolerance in the normal subjects and the diabetic patients.
See Toxno’s References for Jackfruit on Evernote